Hemorrhagic Hereditary Telangiectasia (Rendu-Osler Disease) and Infectious Diseases: An Underestimated Association

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Hereditary Hemorrhagic Telangiectasia (HHT, Osler–Weber–Rendu disease) — Symptoms and Diagnosis

Hereditary hemorrhagic telangiectasia (HHT) or Osler-Weber-Rendu-Disease (OWRD) is a rare autosomal dominant disorder that affects blood vessels and consequently multiple systems resulting in a tendency to bleed. Also known as vascular dysplasia, the condition is more or less diagnosed clinically and has a variable prognosis depending on prompt recognition and severity. However, there is no cur...

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[Ophthalmologic diagnosis of hereditary hemorrhagic telangiectasia or Rendu-Osler-Weber disease].

CASE REPORT Our patient was a 45-year-old woman who had recurrent episodes of hematic epiphora, repeated epistaxes for which no cause was found and a family history of gastric hemorrhage. One of her daughters also suffered from spontaneous hemorrhages. DISCUSSION Hereditary hemorrhagic telangiectasia is rarely diagnosed by an ophthalmologist; however the occurrence of bloody tears occurring s...

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Hereditary Hemorrhagic Telangiectasia (HHT, Osler–Weber–Rendu disease) — Symptoms and Diagnosis

Hereditary hemorrhagic telangiectasia (HHT) or Osler-Weber-Rendu-Disease (OWRD) is a rare autosomal dominant disorder that affects blood vessels and consequently multiple systems resulting in a tendency to bleed. Also known as vascular dysplasia, the condition is more or less diagnosed clinically and has a variable prognosis depending on prompt recognition and severity. However, there is no cur...

متن کامل

Intracranial hemorrhage in infants and children with hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu syndrome).

OBJECTIVE Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular dysplasia. Most cases are caused by mutations in the endoglin gene on chromosome 9 (HHT type 1) or the activin receptor-like kinase 1 gene on chromosome 12 (HHT type 2), which leads to telangiectases and arteriovenous malformations (AVM) of the skin, mucosa, and viscera. Epistaxis is the most frequent presen...

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Exceptional multiplicity of cerebral arteriovenous malformations associated with hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu syndrome).

PURPOSE To describe the clinical and imaging features of seven patients with hereditary hemorrhagic telangiectasia and an exceptional number of cerebral arteriovenous malformations (AVMs). METHODS One hundred thirty-six patients from a dedicated hereditary hemorrhagic telangiectasia clinic were screened systematically for cerebral AVMs by means of MR imaging. Thirty-one were found to have abn...

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ژورنال

عنوان ژورنال: Clinical Infectious Diseases

سال: 2007

ISSN: 1058-4838,1537-6591

DOI: 10.1086/511645